DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 53969-01-0
Molecular formula: C26H18O13
Molecular weight: 538.4
Purity: >95% (HPLC)
Appearance: Red powder.
Solubility: Soluble in DMSO, aqueous acetonitrile or ethanol.
InChiKey: VGXVKHPGBHVPMW-GWQKEKGPSA-N
SMILES: O[C@H]1C[C@@]2(OC3=C(O)C(C(OC(C(OC)=O)=C4)=O)=C4C=C13)CC5=C(O)C(C(C=C(OC)C6=O)=O)=C6C(O)=C5O2
Description:
Rubromycin antibiotic. Antibacterial, antifungal and anti-protozoal agent. Active against Gram-positive bacteria, Gram-negative bacteria and fungi. Telomerase inhibitor (IC50=3µM). Protein synthesis inhibitor. Binds tRNAs with high affinity and specifically inhibits aminoacyl-tRNA formation consequent inhibition of protein synthesis in these microorganisms. Inhibits of all tRNA synthetases. Effectively inhibits bacterial translation and translation in eukaryotic cells. Modest inhibitor of retroviral reverse transcriptase.