bs-75153C
[Life Science]
Rasfonin
DATASHEET
Formulation Liquid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 303156-68-5
Molecular formula: C25H38O6
Molecular weight: 434.6
Purity: >95% (HPLC)
Appearance: Tan to brown viscous liquid (oily).
Solubility: Soluble in ethanol, methanol or DMSO (all 1mg/ml).
InChiKey: OHRGHFXATDKGOV-MDKHPKFKSA-N
SMILES: O=C1O[C@@]([C@H](C[C@@H](C)C/C(C)=C/C)C)([H])C(OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1
Molecular formula: C25H38O6
Molecular weight: 434.6
Purity: >95% (HPLC)
Appearance: Tan to brown viscous liquid (oily).
Solubility: Soluble in ethanol, methanol or DMSO (all 1mg/ml).
InChiKey: OHRGHFXATDKGOV-MDKHPKFKSA-N
SMILES: O=C1O[C@@]([C@H](C[C@@H](C)C/C(C)=C/C)C)([H])C(OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1
Description:
Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in vivo. Robust inhibitor of pancreatic cancers with the K-ras mutation. Reduced Sos1 expression and depressed Ras-MAPK activity.
Size: 500ug,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.