bs-75149C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 3022-92-2

Molecular formula: C23H39N5O5S2

Molecular weight: 529.7

Purity: >95% (HPLC)

Appearance: White solid.

Solubility: Soluble in DMSO.

InChiKey: BEZOVOWRERTMCU-VEXWFWOFSA-N

SMILES: [H][C@]1(NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H]2CSSC[C@@H](NC1=O)C(=O)N2)C(C)C)[C@@H](C)CC

Description:

Peptide antibiotic. Antibcaterial [1]. Plant growth stimulator [2]. Induces root curvature and malformation in plants [3]. Mycotoxin [4]. Prevents interleukin-1 (IL-1) induced endothelial changes by inhibition of protein synthesis [5]. Inhibitor of interleukin-1 beta (IL1 beta) binding to its receptor [6]. Enhancer of cellular fibrinolytic activity [7, 12]. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents [8]. Anticancer compound. Cytotoxic against several cancer cell lines [9]. Antimalarial and antitrypanosomal [10]. Inhibitor of BRAF-mutated melanoma cell lines [11].