DATASHEET
Formulation
Solid
Storage:
Stable for 3 years after receipt when stored at -20°C.
Product Information:
CAS Number: 133343-34-7
Molecular formula: C15H24N2O7S
Molecular weight: 376.4
Purity: >98% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in water (10mM), methanol, ethanol, DMSO, pyridine, acetonitrile or dimethyl formamide. Insoluble in hexane, benzene, chloroform or ethyl acetate.
InChiKey: DAQAKHDKYAWHCG-MJZHQVMOSA-N
SMILES: CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
Description:
Induces neuritogenesis [1, 3]. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex) [2, 4, 7]. Blocks proteasome activity by targeting the catalytic beta-subunit [5]. Apoptosis inducer [4, 6, 7, 10]. Anticancer compound [6, 10, 13]. Upregulates HSP70 and HSP22 [8]. Induces differentiation and inhibits cell cycle progression in several tumor cell lines [9]. Inhibits NF-kappaB activation by inhibiting IkappaB degradation [11]. Cathepsin A inhibitor [12]. beta-Secretase activity inhibitor [14]. Anti-adipogenic [15, 16]. Autophagy inducer [17].
Size:
100ug,200ug,500ug,1mg,
Applications:
Life Science()
For research use only. Not intended for diagnostic or therapeutic use.