bs-75068C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 57817-89-7 (anhydrous)

Molecular formula: C38H60O18 . xH2O

Molecular weight: 804.9 (anhydrous basis)

Purity: >95% (HPLC)

Appearance: White solid.

Solubility: Soluble in water.

InChiKey: UEDUENGHJMELGK-ZBVPAOMMSA-N

SMILES: [H][C@@]12CC[C@@]3(C[C@]1(CC3=C)CC[C@]1([H])[C@@](C)(CCC[C@@]21C)C(=O)O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O)O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O

Description:

Noncaloric natural sweetener, 300 times more potent than sucrose [1]. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity. [2, 4, 6-9, 11]. Antihypertensive. Ca2+ influx inhibitor [3, 6]. Anticancer compound [5]. Chemopreventive [14]. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release [10, 17, 18]. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type hypersensitivity. Increased proliferation in LPS and Con A stimulated B and T cells [12]. Peripheral µ-opioid receptors activator. Important for regulation of glucose homeostasis [15]. Anti-atherosclerotic [16]. Review [13].