bs-75061C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 38778-30-2

Molecular formula: C27H44O8

Molecular weight: 496.6

Purity: >95% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in acetic acid, ethanol, methanol or DMSO. Insoluble in water.

InChiKey: LRJUYAVTHIEHAI-LDJCFVSYSA-N

SMILES: [H][C@@]1(CC[C@@]2(O)C3=CC(=O)[C@]4(O)C[C@@H](O)[C@@H](O)C[C@]4(C)C3[C@H](O)C[C@]12C)[C@@](C)(O)[C@H](O)CCC(C)C

Description:

Potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Analog of ecdysone with similar properties to ponasterone A (Prod. No. bs-75052C). Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Induces apoptosis in cells transfected with wild-type Bax. Induces expression of beta-galactosidase. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest. Major molting hormone in some insects. Has protective effects in plants.