DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 75593-17-8 and 125118-55-0
Molecular formula: C11H11N5O2
Molecular weight: 245.2
Purity: >95% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in DMSO, ethanol or methanol.
InChiKey: JYRJOQGKGMHTOO-VURMDHGXSA-N
SMILES: NC1=NC(=O)\C(N1)=C1/CCNC(=O)C2=C1C=CN2
Description:
Protein kinase C (PKC) inhibitor. Inhibits the ATP binding site [1]. Cytotoxic and insecticidal [2]. G2 DNA damage checkpoint inhibitor. Check point kinases 1 (Chk1) and 2 (Chk2) inhibitor [3, 4, 6]. Does not inhibit ataxia-telangiectasia mutated (ATM) or ATM-Rad3-related proteins [3, 4]. MAP kinase kinase 1 (MEK-1) inhibitor [5]. Interleukin-1 (IL-1) inhibitor. Anti-osteoarthritic [7]. Potential anti-Alzheimer agent [7].