DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 632-85-9
Molecular formula: C16H12O5
Molecular weight: 284.3
Purity: >98% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in DMSO and methanol.
InChiKey: XLTFNNCXVBYBSX-UHFFFAOYSA-N
SMILES: COC1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1
Description:
Anti-inflammatory. Increases nitric oxide (NO) production [1]. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II) [2, 5]. Antioxidant [3]. Anti-viral. Shows anti-hepatitis B virus activity [4]. MCP-1 inhibitor [6]. Shows anxiolytic effect through modulation of the GABA(A) receptor complex [7]. Antifungal [8]. Neuroprotective [9]. Anticancer compound. Apoptosis and cell cycle arrest inducer [10, 12, 14, 17, 18]. Sensitizes TNFalpha- and TRAIL-induced apoptosis [11, 12]. Antiangiogenic [13]. NF-kappaB inhibitor [15]. Telomerase activity inhibitor [16]. CDK9 inhibitor [19]. PI3K-AKT pathway modulator [20]. Autophagy inducer [21].