DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 96829-58-2
Molecular formula: C29H53NO5
Molecular weight: 495.7
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO, ethanol or DMF.
InChiKey: AHLBNYSZXLDEJQ-FWEHEUNISA-N
SMILES: [H]C(=O)N[C@@H](CC(C)C)C(=O)O[C@@H](CCCCCCCCCCC)C[C@@H]1OC(=O)[C@H]1CCCCCC
Description:
Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor [1-3]. Anti-obesity and antihypercholesterolemic compound [2, 5, 11]. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN) [4, 6, 9, 10]. Anti-proliferative [4, 6, 9, 10]. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation [6, 10]. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG [7]. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss [8]. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways [11].
Size:
50mg, , 250 mg , 250 mg
Applications:
Life Science()
For research use only. Not intended for diagnostic or therapeutic use.