bs-75045C
[Life Science]
Streptozotocin
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 18883-66-4
Molecular formula: C8H15N3O7
Molecular weight: 265.2
Purity: >98% (HPLC) | >75% (alpha anomer)
Appearance: Off-white to pale yellow powder.
Solubility: Soluble in water or ethanol.
InChiKey: ZSJLQEPLLKMAKR-GKHCUFPYSA-N
SMILES: CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
Molecular formula: C8H15N3O7
Molecular weight: 265.2
Purity: >98% (HPLC) | >75% (alpha anomer)
Appearance: Off-white to pale yellow powder.
Solubility: Soluble in water or ethanol.
InChiKey: ZSJLQEPLLKMAKR-GKHCUFPYSA-N
SMILES: CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
Description:
Antibiotic [1]. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells [2, 5, 13, 14]. Mutagenic [3, 10]. Potent alkylating agent. Potent DNA methylating agent [4, 10]. Nitric oxide (NO) donor. Vasorelaxant [6]. Cytotoxic to cells that express GLUT2 glucose transporter [7]. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor [8]. Genotoxic. Induces DNA damage. Produces DNA strand breaks [9, 10]. Cell death inducer [15]. Antineoplastic. Anti-cancer agent used in chemotherapy [10, 11]. Induces cell cylce arrest at G2 [12].
Size: 50mg, , 250 mg, 1g , 250 mg, 1g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.