DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 33069-62-4
Molecular formula: C47H51NO14
Molecular weight: 853.9
Purity: >99% (HPLC)
Appearance: White powder.
Solubility: Soluble in DMSO, ethanol or acetonitrile.
InChiKey: RCINICONZNJXQF-MZXODVADSA-N
SMILES: [H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](OC(C)=O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C5=CC=CC=C5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
Description:
Anticancer compound [1, 11, 14]. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma [11, 12]. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin [2, 3, 6, 13, 14]. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase [4, 5, 10, 13]. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) [7-9, 10]. Immunosuppressor. Immunostimulant [15]. Antiproliferative agent for the prevention of restenosis [16]. TRAIL sensitizer [17]
Size:
1mg,5mg,25mg,100mg,
Applications:
Life Science()
For research use only. Not intended for diagnostic or therapeutic use.