bs-75039C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 71678-03-0

Molecular formula: C22H30O4

Molecular weight: 358.5

Purity: >98% (HPLC)

Appearance: Yellow solid.

Solubility: Soluble in methanol, ethanol, DMSO or hexane.

InChiKey: JJWITJNSXCXULM-ZKZNVZPYSA-N

SMILES: [H][C@]12CCCC(=C)[C@]1(C)CC[C@@H](C)[C@]2(C)CC1=C(O)C(=O)C=C(OC)C1=O

Description:

Cytoplasmic microtubule inhibitor [2, 6]. Cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound [1, 11]. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures [2, 6]. Blocks the association of the ADP-ribosylation factor and beta-COP to the Golgi membrane [3, 6]. Blocks protein transport to the plasma membrane and inhibits gap junctional communication [2, 3, 9]. HIV-1 inhibitor [4]. Blocks the cytotoxicity of ricin and diphtheria toxin [5]. S-Adenosylhomocysteinase hydrolase inhibitor and cellular methylations inhibitor [7, 12]. DNA polymerase beta lyase activity inhibitor [8]. Anti-cancer compound. [10].