DATASHEET
Formulation
Film
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 76343-94-7
Molecular formula: C20H29NO5S
Molecular weight: 395.5
Purity: >98% (HPLC)
Appearance: Colorless viscous film
Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).
InChiKey: NSHPHXHGRHSMIK-JRIKCGFMSA-N
SMILES: C[C@@H](CC[C@@H](O[C@]([C@@]1([H])NC(SC1)=O)(O)C2)C[C@H]2O3)/C=C\CC/C(C)=C\C3=O
Description:
Cell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3]. Depolymerizes actin filaments (F-actin) [3]. Less potent than Latrunculin A (Prod. No. bs-75028C). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies [4, 5]. Acts via a different mechanism than cytochalasins.