bs-75028C [Life Science]
Latrunculin A
www.biossusa.com
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DATASHEET

Formulation Film

Storage: Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.

Product Information:

CAS Number: 76343-93-6

Molecular formula: C22H31NO5S

Molecular weight: 421.6

Purity: >97% (HPLC)

Appearance: Colorless viscous film

Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).

InChiKey: DDVBPZROPPMBLW-IZGXTMSKSA-N

SMILES: O=C(SC1)N[C@]1([H])[C@](C2)(O)O[C@@H](C[C@H]2O3)CC[C@H](C)/C=C\C=C\CC/C(C)=C\C3=O

Description:

Cell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3, 6]. Depolymerizes actin filaments (F-actin) [3]. Potent phagocytosis inhibitor [4]. Anticancer compound [7, 8]. Suppresses hypoxia-induced HIF-1 activation in tumor cells [7]. Inhibits tumor cell invasion [7]. Acts via a different mechanism than cytochalasins.

Size: 100ug,500ug,

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.