bs-75024C
[Life Science]
Staurosporine
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 62996-74-1
Molecular formula: C28H26N4O3
Molecular weight: 466.5
Purity: >98% (HPLC)
Appearance: Off-white to yellow solid.
Solubility: Soluble in DMSO, ethyl acetate or dimethyl formamide. Insoluble in water.
InChiKey: HKSZLNNOFSGOKW-FYTWVXJKSA-N
SMILES: [H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
Molecular formula: C28H26N4O3
Molecular weight: 466.5
Purity: >98% (HPLC)
Appearance: Off-white to yellow solid.
Solubility: Soluble in DMSO, ethyl acetate or dimethyl formamide. Insoluble in water.
InChiKey: HKSZLNNOFSGOKW-FYTWVXJKSA-N
SMILES: [H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
Description:
Antibiotic. Antifungal and anti-yeast activity [1]. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation [2]. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, GSK-3beta and Pim-1 kinase [3, 4, 5, 6, 12]. DYRK1A inhibitor (IC50=20nM) [13]. Key apoptosis inducer [7, 8, 10, 11]. Topoisomerase II (Topo II) inhibitor [9].
Size: 100ug,500ug,1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.