DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 99533-80-9
Molecular formula: C27H21N3O5
Molecular weight: 467.5
Purity: >98% (HPLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO, methanol, methylene chloride, ethyl acetate or acetone. Insoluble in water.
InChiKey: KOZFSFOOLUUIGY-SOLYNIJKSA-N
SMILES: [H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
Description:
Antibiotic [1]. PKC, PKA and PKG inhibitor [1, 2, 4]. Shows neurotropic activity by inducing neurite outgrowth [3, 8, 11,16]. Highly potent cell permeable CaM kinase [6] and phosphorylase inhibitor [5]. Tyrosine protein kinase inhibitor of the TRK family [7]. Antiproliferative [9, 10, 13, 15]. Apoptosis inducer [12, 16]. Cell cycle arrest inducer [12]. Potential drug for psoriasis treatment [14].