DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 6805-34-1
Molecular formula: C24H30O3
Molecular weight: 366.5
Purity: >97% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in 100% ethanol, methanol or DMSO.
InChiKey: NJJDBBUWWOAOLD-CFBAGHHKSA-N
SMILES: OC(C1=CC=CC=C1O2)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)C2=O
Description:
Prenylated 4-hydroxycoumarin. Anti-tumor compound [2]. Cytotoxic [2]. Stimulator of tubulin polymerization in vitro [2]. Inhibitor of colchicine binding to tubulin [2]. Antitubercular antibiotic with potent antibacterial activity [3]. Anti-coagulant, pro-haemorrhagic compound with higher activity than warfarin [4]. Shows hepatocyte toxicity [1, 4]. Disrupts mitochondrial membrane potential [5, 6]. Potent L-malate:quinone oxidoreductase (PfMQO) inhibitor in Plasmodium falciparum. Antimalarial.