bs-75013C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 41743-44-6

Molecular formula: C22H30O4

Molecular weight: 358.5

Purity: >98% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO, acetone, dichloromethane or ethyl acetate.

InChiKey: CYSHNJQMYORNJI-YUVXSKOASA-N

SMILES: [H][C@@]12[C@H](CC(C)=CC[C@@]1(C)CC[C@@]2(O)C(C)C)OC(=O)C1=CC=C(O)C=C1

Description:

Potent, naturally occuring non-steroid estrogenic compound. Tool to promote mitochondrial calcium overload and to promote calcium-dependent opening of the mitochondrial permeability transition pore (mPTP) [1, 3, 4]. Strong agonist for estrogen receptor (ER)alpha and agonist/antagonist for ERbeta [2, 8]. Calcium ionophoretic [4, 11] Apoptosis modulator [4]. Antiproliferative [5, 7]. Increases nitric oxide synthase activity and phosphoinositides breakdown in nervous tissue [6]. Shows aphrodisiac and anti-sexual impotence activities [6]. Anti-osteoporotic. Prevents osteoporosis caused by severe estrogen deficiency [9]. Modest AChE inhibitor [10].