bs-7222C
[Life Science]
Takinib
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 322.36
Formula: C18 H18 N4 O2
CAS Number: 1111556-37-6
InChi Key: UOZVVPXKJGOFIG-UHFFFAOYSA-N
InChi: InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
Smiles: CCCN1C(NC(=O)C2C=C(C=CC=2)C(N)=O)=NC2C=CC=CC1=2
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C18 H18 N4 O2
CAS Number: 1111556-37-6
InChi Key: UOZVVPXKJGOFIG-UHFFFAOYSA-N
InChi: InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
Smiles: CCCN1C(NC(=O)C2C=C(C=CC=2)C(N)=O)=NC2C=CC=CC1=2
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is an inhibitor of autophosphorylated and non-phosphorylated TAK1 that binds within the ATP-binding pocket and inhibits by slowing down the rate-limiting step of TAK1 activation.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.