bs-7215C
[Life Science]
dBET6
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 841.37
Formula: C42 H45 Cl N8 O7 S
CAS Number: 1950634-92-0
InChi Key: JGQPZPLJOBHHBK-UFXYQILXSA-N
InChi: InChI=1S/C42H45ClN8O7S/c1-23-24(2)59-42-35(23)37(26-13-15-27(43)16-14-26)46-29(38-49-48-25(3)50(38)42)21-33(53)44-19-8-6-4-5-7-9-20-45-34(54)22-58-31-12-10-11-28-36(31)41(57)51(40(28)56)30-17-18-32(52)47-39(30)55/h10-16,29-30H,4-9,17-22H2,1-3H3,(H,44,53)(H,45,54)(H,47,52,55)/t29-,30?/m0/s1
Smiles: CC1=NN=C2[C@H](CC(=O)NCCCCCCCCNC(=O)COC3C=CC=C4C=3C(=O)N(C3CCC(=O)NC3=O)C4=O)N=C(C3=C(SC(C)=C3C)N12)C1C=CC(Cl)=CC=1
Purity: 98.0
Solubility: DMSO: 100 mg/mL(118.85 mM).
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C42 H45 Cl N8 O7 S
CAS Number: 1950634-92-0
InChi Key: JGQPZPLJOBHHBK-UFXYQILXSA-N
InChi: InChI=1S/C42H45ClN8O7S/c1-23-24(2)59-42-35(23)37(26-13-15-27(43)16-14-26)46-29(38-49-48-25(3)50(38)42)21-33(53)44-19-8-6-4-5-7-9-20-45-34(54)22-58-31-12-10-11-28-36(31)41(57)51(40(28)56)30-17-18-32(52)47-39(30)55/h10-16,29-30H,4-9,17-22H2,1-3H3,(H,44,53)(H,45,54)(H,47,52,55)/t29-,30?/m0/s1
Smiles: CC1=NN=C2[C@H](CC(=O)NCCCCCCCCNC(=O)COC3C=CC=C4C=3C(=O)N(C3CCC(=O)NC3=O)C4=O)N=C(C3=C(SC(C)=C3C)N12)C1C=CC(Cl)=CC=1
Purity: 98.0
Solubility: DMSO: 100 mg/mL(118.85 mM).
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
dBET6 is a novel degrader of BET bromodomain proteins. dBET6 prompts a collapse of global elongation that phenocopies CDK9 inhibition.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.