bs-7189C
[Life Science]
Saracatinib
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 542.03
Formula: C27 H32 Cl N5 O5
CAS Number: 379231-04-6
InChi Key: OUKYUETWWIPKQR-UHFFFAOYSA-N
InChi: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
Smiles: CN1CCN(CCOC2C=C3N=CN=C(NC4=C(Cl)C=CC5OCOC=54)C3=C(C=2)OC2CCOCC2)CC1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C27 H32 Cl N5 O5
CAS Number: 379231-04-6
InChi Key: OUKYUETWWIPKQR-UHFFFAOYSA-N
InChi: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
Smiles: CN1CCN(CCOC2C=C3N=CN=C(NC4=C(Cl)C=CC5OCOC=54)C3=C(C=2)OC2CCOCC2)CC1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.