bs-7142C
[Life Science]
VH 032 amide-PEG5-acid
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 750.9
Formula: C36 H54 N4 O11 S
CAS Number: 2172820-14-1
InChi Key: KEVFVBURAAZURM-ZAPNVNOBSA-N
InChi: InChI=1S/C36H54N4O11S/c1-24-31(52-23-38-24)27-8-6-26(7-9-27)21-37-33(43)29-20-28(41)22-40(29)34(44)32(36(3,4)5)39-30(42)10-11-47-12-13-48-14-15-49-16-17-50-18-19-51-25(2)35(45)46/h6-9,23,25,28-29,32,41H,10-22H2,1-5H3,(H,37,43)(H,39,42)(H,45,46)/t25?,28-,29+,32-/m1/s1
Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOC(C)C(O)=O)C(C)(C)C)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C36 H54 N4 O11 S
CAS Number: 2172820-14-1
InChi Key: KEVFVBURAAZURM-ZAPNVNOBSA-N
InChi: InChI=1S/C36H54N4O11S/c1-24-31(52-23-38-24)27-8-6-26(7-9-27)21-37-33(43)29-20-28(41)22-40(29)34(44)32(36(3,4)5)39-30(42)10-11-47-12-13-48-14-15-49-16-17-50-18-19-51-25(2)35(45)46/h6-9,23,25,28-29,32,41H,10-22H2,1-5H3,(H,37,43)(H,39,42)(H,45,46)/t25?,28-,29+,32-/m1/s1
Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOC(C)C(O)=O)C(C)(C)C)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
VH 032 amide-PEG5-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development. It incorporates an E3 ligase ligand plus a PEG5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.