bs-7134C
[Life Science]
A66
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 393.53
Formula: C17 H23 N5 O2 S2
CAS Number: 1166227-08-2
InChi Key: HBPXWEPKNBHKAX-NSHDSACASA-N
InChi: InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1
Smiles: CC1N=C(NC(=O)N2CCC[C@H]2C(N)=O)SC=1C1=CSC(=N1)C(C)(C)C
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C17 H23 N5 O2 S2
CAS Number: 1166227-08-2
InChi Key: HBPXWEPKNBHKAX-NSHDSACASA-N
InChi: InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1
Smiles: CC1N=C(NC(=O)N2CCC[C@H]2C(N)=O)SC=1C1=CSC(=N1)C(C)(C)C
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
A66 is a potent and highly selective p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity for p110α over other class-I PI3K isoforms. A66 blocks phosphoinositide 3-kinase signalling and tumour growth in certain cell types.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.