DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 413.12
Formula: C19 H13 Cl4 N O
CAS Number: 145888-79-5
InChi Key: GJPXGFGIFQWUOC-ACFHMISVSA-N
InChi: InChI=1S/C19H13Cl4NO/c20-15-3-1-11(7-17(15)22)5-13-9-24-10-14(19(13)25)6-12-2-4-16(21)18(23)8-12/h1-8,24H,9-10H2/b13-5+,14-6+
Smiles: O=C1/C(/CNC/C/1=C\C1=CC(Cl)=C(Cl)C=C1)=C/C1=CC(Cl)=C(Cl)C=C1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
RAMB4, also known as PTP1B-IN-9, is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 selectively reduces the viability of cervical cancer cells independently of HPV genotype via blockade of proteasomal degradation. RAMB4 treatment triggers a Ubiquitin-Proteasome-System (UPS)-stress response without affecting 20S proteasome catalytic activities.