bs-7113C
[Life Science]
LQZ-7I
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 348.35
Formula: C20 H14 F2 N4
CAS Number: 195822-23-2
InChi Key: DKPCKOKYSVPFEB-UHFFFAOYSA-N
InChi: InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H,(H,23,25)(H,24,26)
Smiles: FC1C=CC(=CC=1)NC1=NC2=CC=CC=C2N=C1NC1C=CC(F)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C20 H14 F2 N4
CAS Number: 195822-23-2
InChi Key: DKPCKOKYSVPFEB-UHFFFAOYSA-N
InChi: InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H,(H,23,25)(H,24,26)
Smiles: FC1C=CC(=CC=1)NC1=NC2=CC=CC=C2N=C1NC1C=CC(F)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.