bs-7080C
[Life Science]
NBMPR
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 419.41
Formula: C17 H17 N5 O6 S
CAS Number: 38048-32-7
InChi Key: DYCJFJRCWPVDHY-LSCFUAHRSA-N
InChi: InChI=1S/C17H17N5O6S/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2/t11-,13-,14-,17-/m1/s1
Smiles: [O-][N+](=O)C1C=CC(CSC2N=CN=C3C=2N=CN3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C17 H17 N5 O6 S
CAS Number: 38048-32-7
InChi Key: DYCJFJRCWPVDHY-LSCFUAHRSA-N
InChi: InChI=1S/C17H17N5O6S/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2/t11-,13-,14-,17-/m1/s1
Smiles: [O-][N+](=O)C1C=CC(CSC2N=CN=C3C=2N=CN3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
NBMPR, also known as S-4-nitrophenylmethyl-6-thioinosine, is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1. NBMPR is routinely used at concentrations of 0.10 μM and 0.10 mM to specifically inhibit transport of nucleosides mediated by equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2), respectively. NBMPR at a concentration of 0.10 mM abolishes ABCG2 activity.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.