bs-70279CH

DATASHEET

Host: Chicken

Target Protein: Tau

Specificity: Specific for the ~48, 65 & 75 kDa tau isoforms.

Clonality: Polyclonal

Isotype: IgY

Entrez Gene: 4137

Swiss Prot: P10636

Source: Recombinant full length human tau expressed in and purified from E.Coli.

Purification: Total IgY fraction

Storage Buffer: PBS + 10 mM NaN3.

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliq

Background:

Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.

Size: 100ul

Concentration: Lot Dependent

Cross Reactive Species: Human
Mouse
Rat
Bovine
Pig

For research use only. Not intended for diagnostic or therapeutic use.