bs-70237R

DATASHEET

Host: Rabbit

Target Protein: Rab 3

Specificity: Specific for endogenous levels of the ~27 kDa Rab3 protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 25531

Swiss Prot: P63012

Source: Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat Rab 3, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 27

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Xenopus
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.