bs-70204R

DATASHEET

Host: Rabbit

Target Protein: NSF (N-ethylmaleimide sensitive fusion protein)

Specificity: Specific for endogenous levels of the ~75 kDa NSF protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 60355

Swiss Prot: Q9QUL6

Source: Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat NSF, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

NSF (N-ethylmaleimide sensitive fusion protein) is a critical component of the SNARE (soluble NSF attachment protein receptors) protein complex that is involved in synaptic vesicle trafficking. Specifically, NSF has been found to be essential in membrane fusion. Furthermore, NSF has been recently demonstrated to bind other protein complexes such as AMPA receptor subunits (GluR2), GATE-16, LMA-1 and Rabs suggesting a more diverse role in the assembly of various protein complexes (Whiteheart et al., 2004).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 75

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.