bs-70074R

DATASHEET

Host: Rabbit

Target Protein: Dynamin

Specificity: Specific for endogenous levels of the ~95 kDa dynamin protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1759

Swiss Prot: Q05193

Source: Synthetic peptide corresponding to amino acid residues from the N-terminal region of human dynamin, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001; Graham et al., 2002; Tsuboi et al., 2002). There are 3 known isoforms of Dynamin, each having several splice variants as well. Dynamin I is expressed only in neurons whereas Dynamin II is ubiquitously expressed and Dynamin III is found primarily in the testes. Dynamin 1 is phosphorylated by PKC and dephosphorylated by calcineurin.

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 95

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Bovine
Chicken
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.