bs-70067S

DATASHEET

Host: Sheep

Target Protein: Dopamine ß-Hydroxylase, C-Terminus

Specificity: Specific for endogenous levels of the ~75 kDa DBH protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1621

Swiss Prot: P09172

Source: Synthetic peptide from the C-terminal region of human dopamine β-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 75

Cross Reactive Species: Human
Mouse
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.