bs-70003R

DATASHEET

Host: Rabbit

Target Protein: Adenylate Cyclase III

Specificity: Specific for endogenous levels of the ~160 kDa adenylate cyclase III protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 64508

Swiss Prot: P21932

Source: Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification

Storage Buffer: PBS + 50% glycerol and 5 mm NaN3

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 160, 200

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.