bs-6969C
[Life Science]
GW3965 HCl
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 618.51
Formula: C33 H32 Cl2 F3 N O3
CAS Number: 405911-17-3
InChi Key: NMPUWJFHNOUNQU-UHFFFAOYSA-N
InChi: InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H
Smiles: Cl.OC(=O)CC1=CC(=CC=C1)OCCCN(CC(C1C=CC=CC=1)C1C=CC=CC=1)CC1C=CC=C(C=1Cl)C(F)(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C33 H32 Cl2 F3 N O3
CAS Number: 405911-17-3
InChi Key: NMPUWJFHNOUNQU-UHFFFAOYSA-N
InChi: InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H
Smiles: Cl.OC(=O)CC1=CC(=CC=C1)OCCCN(CC(C1C=CC=CC=1)C1C=CC=CC=1)CC1C=CC=C(C=1Cl)C(F)(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
GW3965 is a liver X receptor agonist. GW3965 represses the production of pro-inflammatory cytokines by murine mast cells. GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro. GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.