bs-6906C
[Life Science]
K02288
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 352.38
Formula: C20 H20 N2 O4
CAS Number: 1431985-92-0
InChi Key: CJLMANFTWLNAKC-UHFFFAOYSA-N
InChi: InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22)
Smiles: COC1C(=CC(=CC=1OC)C1C=C(C=NC=1N)C1C=C(O)C=CC=1)OC
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C20 H20 N2 O4
CAS Number: 1431985-92-0
InChi Key: CJLMANFTWLNAKC-UHFFFAOYSA-N
InChi: InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22)
Smiles: COC1C(=CC(=CC=1OC)C1C=C(C=NC=1N)C1C=C(O)C=CC=1)OC
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
K02288 is a potent inhibitor of BMP signaling. K02288 has in vitro activity against ALK2 at low nanomolar concentrations similar to the current lead compound LDN-193189. K02288 specifically inhibited the BMP-induced Smad pathway without affecting TGF-β signaling and induced dorsalization of zebrafish embryos.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.