bs-6893C
[Life Science]
A83-01 --- an ALK inhibibitor.
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 421.52
Formula: C25 H19 N5 S
CAS Number: 909910-43-6
InChi Key: HIJMSZGHKQPPJS-UHFFFAOYSA-N
InChi: InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
Smiles: CC1=CC=CC(=N1)C1=NN(C=C1C1=CC=NC2=CC=CC=C12)C(=S)NC1C=CC=CC=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: white solid powder
Shelf Life: 2.0 years
Formula: C25 H19 N5 S
CAS Number: 909910-43-6
InChi Key: HIJMSZGHKQPPJS-UHFFFAOYSA-N
InChi: InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
Smiles: CC1=CC=CC(=N1)C1=NN(C=C1C1=CC=NC2=CC=CC=C12)C(=S)NC1C=CC=CC=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: white solid powder
Shelf Life: 2.0 years
Description:
A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity induced by TGF-beta type I receptor ALK-5 and that by activin type IB receptor ALK-4 and nodal type I receptor ALK-7, the kinase domains of which are structurally highly related to those of ALK-5.
Size: 10mg solid, 25mg solid,2mg solid 10mg solid, 25mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.