bs-6821C
[Life Science]
GO-6976
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 378.43
Formula: C24 H18 N4 O
CAS Number: 136194-77-9
InChi Key: VWVYILCFSYNJHF-UHFFFAOYSA-N
InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
Smiles: CN1C2C3=C(C4CNC(=O)C=4C=2C2C=CC=CC1=2)C1=CC=CC=C1N3CCC#N
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C24 H18 N4 O
CAS Number: 136194-77-9
InChi Key: VWVYILCFSYNJHF-UHFFFAOYSA-N
InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
Smiles: CN1C2C3=C(C4CNC(=O)C=4C=2C2C=CC=CC1=2)C1=CC=CC=C1N3CCC#N
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
GO-6976, also known as PD-406976, is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. GO-6976 blocked neurotrophin-induced signaling and autophosphorylation of neurotrophin-specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1-1-trk9 cells.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.