bs-6815C
[Life Science]
N-Desmethyltamoxifen hydrochloride
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 393.95
Formula: C25 H28 Cl N O
CAS Number: 15917-65-4
InChi Key: GMLHJWZEYLTNJW-BJFQDICYSA-N
InChi: InChI=1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
Smiles: Cl.CC/C(=C(\C1C=CC=CC=1)/C1C=CC(=CC=1)OCCNC)/C1C=CC=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C25 H28 Cl N O
CAS Number: 15917-65-4
InChi Key: GMLHJWZEYLTNJW-BJFQDICYSA-N
InChi: InChI=1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
Smiles: Cl.CC/C(=C(\C1C=CC=CC=1)/C1C=CC(=CC=1)OCCNC)/C1C=CC=CC=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.