DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 355.82
Formula: C18 H18 Cl N5 O
CAS Number: 164658-13-3
InChi Key: IYNDTACKOAXKBJ-UHFFFAOYSA-N
InChi: InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)
Smiles: OCCCNC1C=C(C=CN=1)C1C=CN=C(NC2=CC(Cl)=CC=C2)N=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
CGP60474 is a potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respectively). Also displays low micromolar activity at PKCĪ±. Displays reversible G1/S cell cycle arrest in U2-OS cells.