bs-6798R-PerCP [Conjugated Primary Antibody]
Calpain 12 Polyclonal Antibody, PerCP Conjugated
www.biossusa.com
[email protected]
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DATASHEET

Host: Rabbit

Target Protein: Calpain 12

Immunogen Range: 201-310/719


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 147968

Source: KLH conjugated synthetic peptide derived from human Calpain 12

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.

Conjugation: PerCP

Excitation/ Emission: 482nm/677nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 81


Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jae Woong Kim. et al. Concurrent inactivating mutations and expression losses of RGS2, HNF1A, and CAPN12 candidate tumor suppressor genes in colon cancers. PATHOL RES PRACT. 2023 Jan;241:154288Read more>>