bs-6794C

DATASHEET

Formulation Powder

Storage: Store in dry, dark place at -20C for 1 year.

Product Information:

Molecular Weight: 416.55

Formula: C25 H36 O5

CAS Number: 75567-37-2

InChi Key: KIBVFXDTJVSNKX-IFOWAPEYSA-N

InChi: InChI=1S/C25H36O5/c1-7-13(2)22(28)30-21-14(3)10-24-11-16(9-17(12-26)20(27)25(21,24)29)19-18(8-15(24)4)23(19,5)6/h7,9-10,15-16,18-21,26-27,29H,8,11-12H2,1-6H3/b13-7+/t15-,16?,18?,19+,20-,21+,24?,25+/m1/s1

Smiles: CC1(C)[C@@H]2C1C[C@@H](C)C13CC2C=C(CO)[C@@H](O)[C@]1(O)[C@@H](OC(=O)C(C)=CC)C(C)=C3

Purity: 98.0

Solubility: soluble in DMSO, not soluble in water.

Appearance: Solid Power.

Shelf Life: 1.0 years

Description:

Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death. Ingenol Mebutate was approved for the topical treatment of actinic keratosis. Ingenol mebutate has also been found to be useful for reactivating latent HIV virus in cells taken from individuals who have tested negative for signs of the disease following extended courses of anti-retroviral drugs, raising the possibility that this drug may be used to expose the last traces of virus, and thus potentially provide a permanent cure for HIV infection.