bs-6790C
[Life Science]
Enzastaurin
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 515.6
Formula: C32 H29 N5 O2
CAS Number: 170364-57-5
InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N
InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
Smiles: CN1C=C(C2=C(C3=CN(C4CCN(CC5C=CC=CN=5)CC4)C4=CC=CC=C34)C(=O)NC2=O)C2=CC=CC=C12
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C32 H29 N5 O2
CAS Number: 170364-57-5
InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N
InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
Smiles: CN1C=C(C2=C(C3=CN(C4CCN(CC5C=CC=CN=5)CC4)C4=CC=CC=C34)C(=O)NC2=O)C2=CC=CC=C12
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Enzastaurin, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.