bs-6720C
[Life Science]
Lenvatinib Mesylate
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 522.96
Formula: C22 H23 Cl N4 O7 S
CAS Number: 857890-39-2
InChi Key: HWLFIUUAYLEFCT-UHFFFAOYSA-N
InChi: InChI=1S/C21H19ClN4O4.CH4O3S/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11;1-5(2,3)4/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28);1H3,(H,2,3,4)
Smiles: COC1C=C2N=CC=C(OC3=CC(Cl)=C(C=C3)NC(=O)NC3CC3)C2=CC=1C(N)=O.CS(O)(=O)=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C22 H23 Cl N4 O7 S
CAS Number: 857890-39-2
InChi Key: HWLFIUUAYLEFCT-UHFFFAOYSA-N
InChi: InChI=1S/C21H19ClN4O4.CH4O3S/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11;1-5(2,3)4/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28);1H3,(H,2,3,4)
Smiles: COC1C=C2N=CC=C(OC3=CC(Cl)=C(C=C3)NC(=O)NC3CC3)C2=CC=1C(N)=O.CS(O)(=O)=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Lenvatinib Mesylate, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.