bs-6714C
[Life Science]
KN-93 Phosphate
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 599.03
Formula: C26 H32 Cl N2 O8 P S
CAS Number: 1188890-41-6
InChi Key: NNKJTPOXLIILMB-IPZCTEOASA-N
InChi: InChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;
Smiles: CN(CC1C=CC=CC=1N(CCO)S(=O)(=O)C1C=CC(=CC=1)OC)C/C=C/C1C=CC(Cl)=CC=1.OP(O)(O)=O
Purity: 98.0
Solubility: DMSO : 100 mg/mL (166.94 mM; Need ultrasonic)
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C26 H32 Cl N2 O8 P S
CAS Number: 1188890-41-6
InChi Key: NNKJTPOXLIILMB-IPZCTEOASA-N
InChi: InChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;
Smiles: CN(CC1C=CC=CC=1N(CCO)S(=O)(=O)C1C=CC(=CC=1)OC)C/C=C/C1C=CC(Cl)=CC=1.OP(O)(O)=O
Purity: 98.0
Solubility: DMSO : 100 mg/mL (166.94 mM; Need ultrasonic)
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
KN-93 Phosphate is a CaMKII inhibitor. KN-93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN-93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN-93 ameliorates levodopa-induced dyskinesia in a rat model of Parkinson's disease. KN-93 protects rat cerebral cortical neurons from N-methyl-D-aspartic acid-induced injury.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.