bs-6692C
[Life Science]
BMS-5, a Potent LIM kinase inhibitor.
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 431.29
Formula: C17 H14 Cl2 F2 N4 O S
CAS Number: 1338247-35-0
InChi Key: IVUGBSGLHRJSSP-UHFFFAOYSA-N
InChi: InChI=1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8,15H,1-2H3,(H,22,23,26)
Smiles: CC(C)C(=O)NC1=NC=C(S1)C1=CC(=NN1C1=C(Cl)C=CC=C1Cl)C(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C17 H14 Cl2 F2 N4 O S
CAS Number: 1338247-35-0
InChi Key: IVUGBSGLHRJSSP-UHFFFAOYSA-N
InChi: InChI=1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8,15H,1-2H3,(H,22,23,26)
Smiles: CC(C)C(=O)NC1=NC=C(S1)C1=CC(=NN1C1=C(Cl)C=CC=C1Cl)C(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BMS-5 is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.