bs-6679C
[Life Science]
Molidustat
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 314.3
Formula: C13 H14 N8 O2
CAS Number: 1154028-82-6
InChi Key: IJMBOKOTALXLKS-UHFFFAOYSA-N
InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2
Smiles: O=C1C(=CNN1C1C=C(N=CN=1)N1CCOCC1)N1C=CN=N1
Purity: 98.0
Solubility: Soluble in DMSO, DMF, and 1:1 DMF:PBS
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C13 H14 N8 O2
CAS Number: 1154028-82-6
InChi Key: IJMBOKOTALXLKS-UHFFFAOYSA-N
InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2
Smiles: O=C1C(=CNN1C1C=C(N=CN=1)N1CCOCC1)N1C=CN=N1
Purity: 98.0
Solubility: Soluble in DMSO, DMF, and 1:1 DMF:PBS
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.