DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 249.33
Formula: C13 H15 N O2 S
CAS Number: 196309-76-9
InChi Key: VHKZGNPOHPFPER-ONNFQVAWSA-N
InChi: InChI=1S/C13H15NO2S/c1-13(2,3)11-5-7-12(8-6-11)17(15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+
Smiles: CC(C)(C)C1C=CC(=CC=1)S(=O)(=O)/C=C/C#N
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Bay 11-7085, a soluble inhibitor of NK-kappaB activation, has been shown to inhibit cell proliferation and induce apoptosis of a variety of cells. Bay 11-7085 induces apoptosis of ECSCs by suppressing antiapoptotic proteins, and that caspase-3-, -8-, and -9-mediated cascades are involved in this mechanism. Bay 11-7085 could be used as a therapeutic agent for the treatment of endometriosis. Bay 11-7085 protects against gut ischemia-reperfusion injury.