bs-6635C
[Life Science]
GBT-440
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 337.37
Formula: C19 H19 N3 O3
CAS Number: 1446321-46-5
InChi Key: FWCVZAQENIZVMY-UHFFFAOYSA-N
InChi: InChI=1S/C19H19N3O3/c1-13(2)22-16(8-10-21-22)19-14(5-4-9-20-19)12-25-18-7-3-6-17(24)15(18)11-23/h3-11,13,24H,12H2,1-2H3
Smiles: CC(C)N1N=CC=C1C1=NC=CC=C1COC1=CC=CC(O)=C1C=O
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C19 H19 N3 O3
CAS Number: 1446321-46-5
InChi Key: FWCVZAQENIZVMY-UHFFFAOYSA-N
InChi: InChI=1S/C19H19N3O3/c1-13(2)22-16(8-10-21-22)19-14(5-4-9-20-19)12-25-18-7-3-6-17(24)15(18)11-23/h3-11,13,24H,12H2,1-2H3
Smiles: CC(C)N1N=CC=C1C1=NC=CC=C1COC1=CC=CC(O)=C1C=O
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
GBT-440, is a hemoglobin S allosteric modulator. GBT440 Inhibits Sickling of Sickle Cell Trait Blood Under In Vitro Conditions Mimicking Strenuous Exercise. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.