bs-6627C
[Life Science]
WZB117
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 368.31
Formula: C20 H13 F O6
CAS Number: 1223397-11-2
InChi Key: FRSWCCBXIHFKKY-UHFFFAOYSA-N
InChi: InChI=1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
Smiles: OC1C=C(C=CC=1)C(=O)OC1C(F)=CC=CC=1OC(=O)C1=CC(O)=CC=C1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C20 H13 F O6
CAS Number: 1223397-11-2
InChi Key: FRSWCCBXIHFKKY-UHFFFAOYSA-N
InChi: InChI=1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
Smiles: OC1C=C(C=CC=1)C(=O)OC1C(F)=CC=CC=1OC(=O)C1=CC(O)=CC=C1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
WZB117 is a potent Glut1 inhibitor. Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation. Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin. WZB117 is a prototype for further development of anticancer therapeutics targeting Glut1-mediated glucose transport and glucose metabolism.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.