bs-6626C
[Life Science]
MGL-3196
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 435.22
Formula: C17 H12 Cl2 N6 O4
CAS Number: 920509-32-6
InChi Key: FDBYIYFVSAHJLY-UHFFFAOYSA-N
InChi: InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28)
Smiles: CC(C)C1=CC(=NNC1=O)OC1C(Cl)=CC(=CC=1Cl)N1N=C(C#N)C(=O)NC1=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C17 H12 Cl2 N6 O4
CAS Number: 920509-32-6
InChi Key: FDBYIYFVSAHJLY-UHFFFAOYSA-N
InChi: InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28)
Smiles: CC(C)C1=CC(=NNC1=O)OC1C(Cl)=CC(=CC=1Cl)N1N=C(C#N)C(=O)NC1=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
MGL-3196, also known as Resmetirom, is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor β (THR-β) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor α (THR-α).
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.