bs-66045C
[Life Science]
LSD1-C76, LSD1 Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 295.38
Formula: C19 H21 N O2
CAS Number: 1235864-15-9
InChi Key: PAXGPAVOMLKKDQ-ZMKYACIDSA-N
InChi: InChI=1S/C19H21NO2/c1-13(15-7-8-18-19(11-15)22-10-9-21-18)20-17-12-16(17)14-5-3-2-4-6-14/h2-8,11,13,16-17,20H,9-10,12H2,1H3/t13?,16-,17+/m0/s1
Smiles: CC(N[C@@H]1C[C@H]1C1C=CC=CC=1)C1=CC2OCCOC=2C=C1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C19 H21 N O2
CAS Number: 1235864-15-9
InChi Key: PAXGPAVOMLKKDQ-ZMKYACIDSA-N
InChi: InChI=1S/C19H21NO2/c1-13(15-7-8-18-19(11-15)22-10-9-21-18)20-17-12-16(17)14-5-3-2-4-6-14/h2-8,11,13,16-17,20H,9-10,12H2,1H3/t13?,16-,17+/m0/s1
Smiles: CC(N[C@@H]1C[C@H]1C1C=CC=CC=1)C1=CC2OCCOC=2C=C1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
LSD1-C76 is the most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor reported to date. It inhibits LSD1 with an IC50 ~5 nM, but not monoamine oxidase proteins MAO-A and MAO-B (>5 µM). As LSD1 plays an important role in the epigenetic control of gene expression in normal development and cancer progression, LSD1-C76 serves as a very useful chemical probe to study the target biology.
Size: 10mg solid, 2mg solid ,10 mM in DMSO (0.678 10mg solid, 2mg solid ,10 mM in DMSO (0.678 mL)
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.